MORG1 Antikörper (AA 64-315) (Biotin)

Produktnummer ABIN7175711

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MORG1 in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MORG1 Antikörper (AA 64-315) (Biotin) (ABIN7175711)

Target: MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MORG1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-MORG1 Antikörper (Biotin)

Bindungsspezifität: AA 64-315

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human WD repeat domain-containing protein 83 protein (64-315AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MORG1

Target: MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))

Andere Bezeichnung: WDR83

Hintergrund:

Background: Molecular scaffold protein for various multimeric protein complexes. Acts as a module in the assembly of a multicomponent scaffold for the ERK pathway, linking ERK responses to specific agonists. At low concentrations it enhances ERK activation, whereas high concentrations lead to the inhibition of ERK activation. Also involved in response to hypoxia by acting as a negative regulator of HIF1A/HIF-1-alpha via its interaction with EGLN3/PHD3. May promote degradation of HIF1A. May act by recruiting signaling complexes to a specific upstream activator (By similarity). May also be involved in pre-mRNA splicing.

Aliases: MAPK organizer 1 antibody, MGC4238 antibody, Mitogen activated protein kinase organizer 1 antibody, Mitogen-activated protein kinase organizer 1 antibody, MORG 1 antibody, WD repeat domain-containing protein 83 antibody, wdr83 antibody, WDR83_HUMAN antibody

UniProt: Q9BRX9