WDFY3 Antikörper (AA 1-100)

Produktnummer ABIN7175699

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch WDFY3 in ELISA, IF und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für WDFY3 Antikörper (AA 1-100) (ABIN7175699)

Target: WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WDFY3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Produktdetails anti-WDFY3 Antikörper

Bindungsspezifität: AA 1-100

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human WD repeat and FYVE domain-containing protein 3 protein (1-100AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu WDFY3

Target: WDFY3 (WD Repeat and FYVE Domain Containing 3 (WDFY3))

Andere Bezeichnung: WDFY3

Hintergrund:

Background: Required for selective autophagy (aggrephagy) but not for autophagic degradation of bulk cytospol in response to starvation. Involved in the formation and degradation of cytoplasmic polyubiquitin-containing bodies (p62 bodies, ALIS/aggresome-like induced structures). May play a role as adaptor or scaffolding protein by promoting the association of the E3-like ligase ATG12-ATG5-ATG16L and LC3 to ubiquitinated target substrate. The association with GABARAP is required for its recruitment to LC3B-positive p62 bodies suggesting a role in targeting certain p62 structures for clearance. Involved in midbody ring degradation.

Aliases: WDFY3 antibody, KIAA0993 antibody, WD repeat and FYVE domain-containing protein 3 antibody, Autophagy-linked FYVE protein antibody, Alfy antibody

UniProt: Q8IZQ1