HSD17B12 Antikörper (AA 40-181)

Produktnummer ABIN7175449

Dieses Anti-HSD17B12-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HSD17B12 in WB, IHC, ELISA und IF. Geeignet für Human.

Kurzübersicht für HSD17B12 Antikörper (AA 40-181) (ABIN7175449)

Target: HSD17B12 (Hydroxysteroid (17-Beta) Dehydrogenase 12 (HSD17B12))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSD17B12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-HSD17B12 Antikörper

Bindungsspezifität: AA 40-181

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Very-long-chain 3-oxoacyl-CoA reductase protein (40-181AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu HSD17B12

Target: HSD17B12 (Hydroxysteroid (17-Beta) Dehydrogenase 12 (HSD17B12))

Andere Bezeichnung: HSD17B12

Hintergrund:

Background: Catalyzes the second of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme has a 3-ketoacyl-CoA reductase activity, reducing 3-ketoacyl-CoA to 3-hydroxyacyl-CoA, within each cycle of fatty acid elongation. Thereby, it may participate to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May also catalyze the transformation of estrone (E1) into estradiol (E2) and play a role in estrogen formation.

Aliases: 12,3-ketoacyl-CoA reductase,short chain antibody, 17 beta HSD 12 antibody, 17 beta hydroxysteroid dehydrogenase 12 antibody, 17-@beta-HSD XII antibody, 17-@beta-hydroxysteroid dehydrogenase XII antibody, 17-beta-HSD 12 antibody, 17-beta-hydroxysteroid dehydrogenase 12 antibody, 17beta HSD type 12 antibody, 3 ketoacyl CoA reductase antibody, 3-ketoacyl-CoA reductase antibody, DHB12_HUMAN antibody, Estradiol 17 beta dehydrogenase 12 antibody, Estradiol 17-beta-dehydrogenase 12 antibody, HSD17B12 antibody, Hydroxysteroid (17-beta) dehydrogenase 12 antibody, KAR antibody, KIK-I antibody, Kik1 antibody, SDR12C1 antibody, Short chain dehydrogenase/reductase family 12C member 1 antibody, Steroid dehydrogenase homolog antibody

UniProt: Q53GQ0

Pathways: Steroid Hormone Biosynthesis