PTPLAD1 Antikörper (AA 1-145)

Produktnummer ABIN7175445

Der Kaninchen Polyklonal Anti-PTPLAD1-Antikörper wurde für ELISA und IHC validiert. Er ist geeignet, PTPLAD1 in Proben von Human zu detektieren.

Kurzübersicht für PTPLAD1 Antikörper (AA 1-145) (ABIN7175445)

Target: PTPLAD1 (Protein tyrosine Phosphatase-Like A Domain Containing 1 (PTPLAD1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPLAD1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-PTPLAD1 Antikörper

Bindungsspezifität: AA 1-145

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 protein (1-145AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PTPLAD1

Target: PTPLAD1 (Protein tyrosine Phosphatase-Like A Domain Containing 1 (PTPLAD1))

Andere Bezeichnung: HACD3

Hintergrund:

Background: Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates in the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. May be involved in Rac1-signaling pathways leading to the modulation of gene expression. Promotes insulin receptor/INSR autophosphorylation and is involved in INSR internalization (PubMed:25687571).

Aliases: HACD3 antibody, BIND1 antibody, PTPLAD1 antibody, Very-long-chain antibody, 3R)-3-hydroxyacyl-CoA dehydratase 3 antibody, EC 4.2.1.134 antibody, 3-hydroxyacyl-CoA dehydratase 3 antibody, HACD3 antibody, Butyrate-induced protein 1 antibody, B-ind1 antibody, hB-ind1 antibody, Protein-tyrosine phosphatase-like A domain-containing protein 1 antibody

UniProt: Q9P035