VPS52 Antikörper (AA 277-377)

Produktnummer ABIN7175328

Der Kaninchen Polyklonal Anti-VPS52-Antikörper wurde für ELISA und IHC validiert. Er ist geeignet, VPS52 in Proben von Human zu detektieren.

Kurzübersicht für VPS52 Antikörper (AA 277-377) (ABIN7175328)

Target: VPS52 (Vacuolar Protein Sorting 52 Homolog (VPS52))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VPS52 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-VPS52 Antikörper

Bindungsspezifität: AA 277-377

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Vacuolar protein sorting-associated protein 52 homolog protein (277-377AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu VPS52

Target: VPS52 (Vacuolar Protein Sorting 52 Homolog (VPS52))

Andere Bezeichnung: VPS52

Hintergrund:

Background: Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (PubMed:15878329, PubMed:18367545). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061).

Aliases: VPS52 antibody, SACM2LVacuolar protein sorting-associated protein 52 homolog antibody, SAC2 suppressor of actin mutations 2-like protein antibody

UniProt: Q8N1B4