VPS51 Antikörper (AA 595-673)

Produktnummer ABIN7175324

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch VPS51 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für VPS51 Antikörper (AA 595-673) (ABIN7175324)

Target: VPS51 (Vacuolar Protein Sorting 51 Homolog (VPS51))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VPS51 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-VPS51 Antikörper

Bindungsspezifität: AA 595-673

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Vacuolar protein sorting-associated protein 51 homolog protein (595-673AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu VPS51

Target: VPS51 (Vacuolar Protein Sorting 51 Homolog (VPS51))

Andere Bezeichnung: VPS51

Hintergrund:

Background: Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. VPS51 participates in retrograde transport of acid hydrolase receptors, likely by promoting tethering and SNARE-dependent fusion of endosome-derived carriers to the TGN (PubMed:20685960). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061).

Aliases: ANG2 antibody, ANG3 antibody, Another new gene 2 protein antibody, C11orf3 antibody, chromosome 11 open reading frame 2 antibody, Fat free homolog antibody, ffr antibody, FFR_HUMAN antibody, FFR|FLJ13879 antibody, FLJ36472 antibody, Protein fat-free homolog antibody, Vacuolar protein sorting 51 homolog antibody, VPS51 antibody

UniProt: Q9UID3