VPS33B Antikörper (AA 348-617)

Produktnummer ABIN7175312

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch VPS33B in IHC und ELISA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für VPS33B Antikörper (AA 348-617) (ABIN7175312)

Target: VPS33B (Vacuolar Protein Sorting-Associated Protein 33B (VPS33B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VPS33B Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktdetails anti-VPS33B Antikörper

Bindungsspezifität: AA 348-617

Verwendungszweck: VPS33B Antibody

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Vacuolar protein sorting-associated protein 33B protein (348-617AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu VPS33B

Target: VPS33B (Vacuolar Protein Sorting-Associated Protein 33B (VPS33B))

Andere Bezeichnung: VPS33B

Hintergrund:

Background: May play a role in vesicle-mediated protein trafficking to lysosomal compartments and in membrane docking/fusion reactions of late endosomes/lysosomes. Mediates phagolysosomal fusion in macrophages (PubMed:18474358). Proposed to be involved in endosomal maturation implicating VIPAS39. In epithelial cells, the VPS33B:VIPAS39 complex may play a role in the apical recycling pathway and in the maintenance of the apical-basolateral polarity (PubMed:20190753). Seems to be involved in the sorting of specific cargos from the trans-Golgi network to alpha-granule-destined multivesicular bodies (MVBs) promoting MVBs maturation in megakaryocytes (By similarity).

Aliases: VPS33BVacuolar protein sorting-associated protein 33B antibody, hVPS33B antibody

UniProt: Q9H267