Myosin XVIIIA Antikörper (AA 1849-2054)

Produktnummer ABIN7174981

Dieses Anti-Myosin XVIIIA-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Myosin XVIIIA in ELISA und IHC. Geeignet für Human.

Kurzübersicht für Myosin XVIIIA Antikörper (AA 1849-2054) (ABIN7174981)

Target: Myosin XVIIIA (MYO18A)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Myosin XVIIIA Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-Myosin XVIIIA Antikörper

Bindungsspezifität: AA 1849-2054

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Unconventional myosin-XVIIIa protein (1849-2054AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Myosin XVIIIA

Target: Myosin XVIIIA (MYO18A)

Andere Bezeichnung: MYO18A

Hintergrund:

Background: May link Golgi membranes to the cytoskeleton and participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus (PubMed:19837035, PubMed:23345592). Alternatively, in concert with LURAP1 and CDC42BPA/CDC42BPB, has been involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160). May be involved in the maintenance of the stromal cell architectures required for cell to cell contact (By similarity). Regulates trafficking, expression, and activation of innate immune receptors on macrophages. Plays a role to suppress inflammatory responsiveness of macrophages via a mechanism that modulates CD14 trafficking (PubMed:25965346). Acts as a receptor of surfactant-associated protein A (SFTPA1/SP-A) and plays an important role in internalization and clearance of SFTPA1-opsonized S.aureus by alveolar macrophages (PubMed:16087679, PubMed:21123169). Strongly enhances natural killer cell cytotoxicity (PubMed:27467939).

Aliases: MYO18A antibody, CD245 antibody, KIAA0216 antibody, MYSPDZ antibody, Unconventional myosin-XVIIIa antibody, Molecule associated with JAK3 N-terminus antibody, MAJN antibody, Myosin containing a PDZ domain antibody, Surfactant protein receptor SP-R210 antibody, SP-R210 antibody

UniProt: Q92614