Ube2t Antikörper (AA 1-197)

Produktnummer ABIN7174485

Der Kaninchen Polyklonal Anti-Ube2t-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, Ube2t in Proben von Human zu detektieren.

Kurzübersicht für Ube2t Antikörper (AA 1-197) (ABIN7174485)

Target: Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ube2t Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-Ube2t Antikörper

Bindungsspezifität: AA 1-197

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Ubiquitin-conjugating enzyme E2 T protein (1-197AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Ube2t

Target: Ube2t (Ubiquitin-Conjugating Enzyme E2T (Ube2t))

Andere Bezeichnung: UBE2T

Hintergrund:

Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes monoubiquitination. Involved in mitomycin-C (MMC)-induced DNA repair: acts as a specific E2 ubiquitin-conjugating enzyme for the Fanconi anemia complex by associating with E3 ubiquitin-protein ligase FANCL and catalyzing monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCL and FANCI. May contribute to ubiquitination and degradation of BRCA1. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer \\\'Lys-11\\\'-, \\\'Lys-27\\\'-, \\\'Lys-48\\\'- and \\\'Lys-63\\\'-linked polyubiquitination.

Aliases: Cell proliferation inducing gene 50 protein antibody, Cell proliferation-inducing gene 50 protein antibody, HSPC150 antibody, HSPC150 protein similar to ubiquitin conjugating enzyme antibody, PIG50 antibody, Ube2t antibody, UBE2T_HUMAN antibody, Ubiquitin carrier protein T antibody, Ubiquitin conjugating enzyme antibody, ubiquitin conjugating enzyme E2 T antibody, Ubiquitin conjugating enzyme E2T antibody, Ubiquitin protein ligase T antibody, Ubiquitin-conjugating enzyme E2 T antibody, Ubiquitin-protein ligase T antibody

UniProt: Q9NPD8

Pathways: Chromatin Binding