UBE2L3 Antikörper (AA 1-154)

Produktnummer ABIN7174468

Dieses Anti-UBE2L3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von UBE2L3 in WB, IHC, ELISA und IF. Geeignet für Human.

Kurzübersicht für UBE2L3 Antikörper (AA 1-154) (ABIN7174468)

Target: UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE2L3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-UBE2L3 Antikörper

Bindungsspezifität: AA 1-154

Kreuzreaktivität: Human, Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Ubiquitin-conjugating enzyme E2 L3 protein (1-154AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu UBE2L3

Target: UBE2L3 (Ubiquitin-Conjugating Enzyme E2L 3 (UBE2L3))

Andere Bezeichnung: UBE2L3

Hintergrund:

Background: Ubiquitin-conjugating enzyme E2 that specifically acts with HECT-type and RBR family E3 ubiquitin-protein ligases. Does not function with most RING-containing E3 ubiquitin-protein ligases because it lacks intrinsic E3-independent reactivity with lysine: in contrast, it has activity with the RBR family E3 enzymes, such as PARK2 and ARIH1, that function like function like RING-HECT hybrids. Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes \\\'Lys-11\\\'-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down-regulated during the S-phase it is involved in progression through the cell cycle. Regulates nuclear hormone receptors transcriptional activity. May play a role in myelopoiesis.

Aliases: E2 F1 antibody, L UBC antibody, L-UBC antibody, UB2L3_HUMAN antibody, UBCE7 antibody, UbcH7 antibody, UbcM4 antibody, Ube2l3 antibody, Ubiquitin carrier protein L3 antibody, Ubiquitin conjugating enzyme E2 L3 antibody, Ubiquitin protein ligase L3 antibody, Ubiquitin-conjugating enzyme E2 L3 antibody, Ubiquitin-conjugating enzyme E2-F1 antibody, Ubiquitin-protein ligase L3 antibody

UniProt: P68036