USP5 Antikörper (C-Term) (FITC)

Produktnummer ABIN7174350

Der Kaninchen Polyklonal Anti-USP5-Antikörper wurde für validiert. Er ist geeignet, USP5 in Proben von Human zu detektieren.

Kurzübersicht für USP5 Antikörper (C-Term) (FITC) (ABIN7174350)

Target: USP5 (Ubiquitin Specific Peptidase 5 (USP5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser USP5 Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Produktdetails anti-USP5 Antikörper (FITC)

Bindungsspezifität: AA 201-500, C-Term

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Ubiquitin carboxyl-terminal hydrolase 5 protein (201-500AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu USP5

Target: USP5 (Ubiquitin Specific Peptidase 5 (USP5))

Andere Bezeichnung: USP5

Hintergrund:

Background: Cleaves linear and branched multiubiquitin polymers with a marked preference for branched polymers. Involved in unanchored \'Lys-48\'-linked polyubiquitin disassembly. Binds linear and \'Lys-63\'-linked polyubiquitin with a lower affinity. Knock-down of USP5 causes the accumulation of p53/TP53 and an increase in p53/TP53 transcriptional activity because the unanchored polyubiquitin that accumulates is able to compete with ubiquitinated p53/TP53 but not with MDM2 for proteasomal recognition.

Aliases: Deubiquitinating enzyme 5 antibody, Isopeptidase T antibody, ISOT 1 antibody, ISOT antibody, Ubiquitin carboxyl-terminal hydrolase 5 antibody, Ubiquitin isopeptidase T antibody, Ubiquitin specific peptidase 5 (isopeptidase T) antibody, Ubiquitin specific peptidase 5 antibody, Ubiquitin specific processing protease 5 antibody, Ubiquitin specific protease 5 (isopeptidase T) antibody, Ubiquitin specific protease 5 (ubiquitin isopeptidase T) antibody, Ubiquitin thioesterase 5 antibody, Ubiquitin thiolesterase 5 antibody, Ubiquitin-specific-processing protease 5 antibody, UBP5_HUMAN antibody, Usp5 antibody

UniProt: P45974