UBIAD1 Antikörper (AA 1-82) (HRP)

Produktnummer ABIN7174223

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch UBIAD1 in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für UBIAD1 Antikörper (AA 1-82) (HRP) (ABIN7174223)

Target: UBIAD1 (UbiA Prenyltransferase Domain Containing 1 (UBIAD1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBIAD1 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Produktdetails anti-UBIAD1 Antikörper (HRP)

Bindungsspezifität: AA 1-82

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human UbiA prenyltransferase domain-containing protein 1 protein (1-82AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu UBIAD1

Target: UBIAD1 (UbiA Prenyltransferase Domain Containing 1 (UBIAD1))

Andere Bezeichnung: UBIAD1

Hintergrund:

Background: Prenyltransferase that mediates the formation of menaquinone-4 (MK-4) and coenzyme Q10. MK-4 is a vitamin K2 isoform present at high concentrations in the brain, kidney and pancreas, and is required for endothelial cell development. Mediates the conversion of phylloquinone (PK) into MK-4, probably by cleaving the side chain of phylloquinone (PK) to release 2-methyl-1,4-naphthoquinone (menadione, K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4. Also plays a role in cardiovascular development independently of MK-4 biosynthesis, by acting as a coenzyme Q10 biosyntetic enzyme: coenzyme Q10, also named ubiquinone, plays a important antioxidant role in the cardiovascular system. Mediates biosynthesis of coenzyme Q10 in the Golgi membrane, leading to protect cardiovascular tissues from NOS3/eNOS-dependent oxidative stress.

Aliases: RP4-796F18.1 antibody, SCCD antibody, TERE 1 antibody, tere1 antibody, Transitional epithelia response protein antibody, Transitional epithelial response protein 1 antibody, UbiA prenyltransferase domain containing 1 antibody, UbiA prenyltransferase domain containing protein 1 antibody, UbiA prenyltransferase domain-containing protein 1 antibody, UBIA1_HUMAN antibody, UBIAD 1 antibody, Ubiad1 antibody

UniProt: Q9Y5Z9