TUSC3 Antikörper (AA 42-196) (FITC)

Produktnummer ABIN7173932

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TUSC3 in . Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TUSC3 Antikörper (AA 42-196) (FITC) (ABIN7173932)

Target: TUSC3 (Tumor Suppressor Candidate 3 (TUSC3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TUSC3 Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Produktdetails anti-TUSC3 Antikörper (FITC)

Bindungsspezifität: AA 42-196

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Tumor suppressor candidate 3 protein (42-196AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TUSC3

Target: TUSC3 (Tumor Suppressor Candidate 3 (TUSC3))

Andere Bezeichnung: TUSC3

Hintergrund:

Background: Acts as accessory component of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Involved in N-glycosylation of STT3B-dependent substrates. Specifically required for the glycosylation of a subset of acceptor sites that are near cysteine residues, in this function seems to act redundantly with MAGT1. In its oxidized form proposed to form transient mixed disulfides with a glycoprotein substrate to facilitate access of STT3B to the unmodified acceptor site. Has also oxidoreductase-independent functions in the STT3B-containing OST complex possibly involving substrate recognition.

Aliases: TUSC3 antibody, N33Tumor suppressor candidate 3 antibody, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3 antibody, Oligosaccharyl transferase subunit TUSC3 antibody, Magnesium uptake/transporter TUSC3 antibody, Protein N33 antibody

UniProt: Q13454

Pathways: Cell RedoxHomeostasis