TSC22D3 Antikörper (AA 58-134) (HRP)

Produktnummer ABIN7173629

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TSC22D3 in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TSC22D3 Antikörper (AA 58-134) (HRP) (ABIN7173629)

Target: TSC22D3 (TSC22 Domain Family, Member 3 (TSC22D3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TSC22D3 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Produktdetails anti-TSC22D3 Antikörper (HRP)

Bindungsspezifität: AA 58-134

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human TSC22 domain family protein 3 protein (58-134AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TSC22D3

Target: TSC22D3 (TSC22 Domain Family, Member 3 (TSC22D3))

Andere Bezeichnung: TSC22D3

Hintergrund:

Background: Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities. Isoform 1 inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcriptional activity resulting in reduced expression of MYOG.

Aliases: Delta sleep-inducing peptide immunoreactor antibody, DIP antibody, DSIP immunoreactive leucine zipper protein antibody, DSIP-immunoreactive peptide antibody, Dsip1 antibody, Dsipi antibody, GILZ antibody, Glucocorticoid-induced leucine zipper protein antibody, hDIP antibody, Protein DIP antibody, T22D3_HUMAN antibody, TSC-22-like protein antibody, TSC-22-related protein antibody, TSC-22R antibody, TSC22 domain family protein 3 antibody, TSC22 domain family, member 3 antibody, TSC22 related inducible leucine zipper 3 antibody, TSC22D3 antibody

UniProt: Q99576