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TMEM59 Antikörper (AA 59-201)

Dieses Rabbit Polyclonal-Antikörper erkennt spezifisch TMEM59 in WB, ELISA, IF. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7173245

Kurzübersicht für TMEM59 Antikörper (AA 59-201) (ABIN7173245)

Target

Alle TMEM59 Antikörper anzeigen
TMEM59 (Transmembrane Protein 59 (TMEM59))

Reaktivität

  • 15
  • 12
Human

Wirt

  • 27
Kaninchen

Klonalität

  • 27
Polyklonal

Konjugat

  • 9
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser TMEM59 Antikörper ist unkonjugiert

Applikation

  • 23
  • 13
  • 13
  • 9
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • Bindungsspezifität

    • 15
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 59-201

    Kreuzreaktivität

    Human

    Aufreinigung

    >95%, Protein G purified

    Immunogen

    Recombinant Human Transmembrane protein 59 protein (59-201AA)

    Isotyp

    IgG
  • Applikationshinweise

    Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    TMEM59 (Transmembrane Protein 59 (TMEM59))

    Andere Bezeichnung

    TMEM59

    Hintergrund

    Background: Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy (PubMed:27273576, PubMed:23376921). Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP (PubMed:20427278). Inhibits APP transport to the cell surface and further shedding (PubMed:20427278).

    Aliases: C1orf8 antibody, HSPC001 antibody, Liver membrane-bound protein antibody, TMEM59 antibody, TMEM59 transmembrane protein 59 antibody, TMM59_HUMAN antibody, Transmembrane protein 59 antibody

    UniProt

    Q9BXS4
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