P4HTM Antikörper (AA 82-563) (Biotin)
Kurzübersicht für P4HTM Antikörper (AA 82-563) (Biotin) (ABIN7173000)
Target
Alle P4HTM Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 82-563
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Transmembrane prolyl 4-hydroxylase protein (82-563AA)
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))
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Andere Bezeichnung
- P4HTM
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Hintergrund
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Background: Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at \'Pro-402\' and \'Pro-564\'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.
Aliases: EGLN4 antibody, HIF PH4 antibody, HIF Prolyl Hydroxylase 4 antibody, HIF prolyl hydroxylase PH 4 antibody, HIF prolyl hydroxylase PH4 antibody, HIF-PH4 antibody, HIF-prolyl hydroxylase 4 antibody, HIFPH4 antibody, HPH 4 antibody, HPH-4 antibody, Hypoxia inducible factor prolyl 4 hydroxylase antibody, Hypoxia-inducible factor prolyl hydroxylase 4 antibody, P4H with transmembrane domain antibody, P4H-TM antibody, P4htm antibody, P4HTM_HUMAN antibody, PH 4 antibody, PH4 antibody, PHD 4 antibody, Proline 4 hydroxylase antibody, prolyl 4-hydroxylase antibody, Transmembrane prolyl 4-hydroxylase antibody
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UniProt
- Q9NXG6
Target
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