Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

TMED2 Antikörper (AA 26-111) (HRP)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TMED2 in ELISA. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7172978

Kurzübersicht für TMED2 Antikörper (AA 26-111) (HRP) (ABIN7172978)

Target

Alle TMED2 Antikörper anzeigen
TMED2 (Transmembrane Emp24 Domain Trafficking Protein 2 (TMED2))

Reaktivität

  • 34
  • 16
  • 12
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 34
Kaninchen

Klonalität

  • 34
Polyklonal

Konjugat

  • 19
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser TMED2 Antikörper ist konjugiert mit HRP

Applikation

  • 23
  • 16
  • 15
  • 4
  • 1
  • 1
ELISA
  • Bindungsspezifität

    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 26-111

    Kreuzreaktivität

    Human

    Aufreinigung

    >95%, Protein G purified

    Immunogen

    Recombinant Human Transmembrane emp24 domain-containing protein 2 protein (26-111AA)

    Isotyp

    IgG
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    TMED2 (Transmembrane Emp24 Domain Trafficking Protein 2 (TMED2))

    Andere Bezeichnung

    TMED2

    Hintergrund

    Background: Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway but also in post-Golgi membranes. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED10 as their cargo receptor, the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft-like microdomains of the ER. Recognizes GPI anchors structural remodeled in the ER by PGAP1 and MPPE1. In COPI vesicle-mediated retrograde transport inhibits the GTPase-activating activity of ARFGAP1 towards ARF1 thus preventing immature uncoating and allowing cargo selection to take place. Involved in trafficking of G protein-coupled receptors (GPCRs). Regulates F2RL1, OPRM1 and P2RY4 exocytic trafficking from the Golgi to the plasma membrane thus contributing to receptor resensitization. Facilitates CASR maturation and stabilization in the early secretory pathway and increases CASR plasma membrane targeting. Proposed to be involved in organization of intracellular membranes such as the maintenance of the Golgi apparatus. May also play a role in the biosynthesis of secreted cargo such as eventual processing.

    Aliases: coated vesicle membrane protein antibody, Membrane protein p24A antibody, p24 antibody, p24 family protein beta-1 antibody, P24A antibody, p24beta1 antibody, RNP24 antibody, Sid 394 antibody, Sid394 antibody, TMED2 antibody, TMED2_HUMAN antibody, transmembrane emp24 domain trafficking protein 2 antibody, Transmembrane emp24 domain-containing protein 2 antibody

    UniProt

    Q15363
Sie sind hier:
Chat with us!