TEAD3 Antikörper (AA 112-435)

Produktnummer ABIN7172763

Produktdetails anti-TEAD3 Antikörper

Target: TEAD3 (TEA Domain Family Member 3 (TEAD3))

Bindungsspezifität: AA 112-435

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TEAD3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Transcriptional enhancer factor TEF-5 protein (112-435AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:500-1:1000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TEAD3

Target: TEAD3 (TEA Domain Family Member 3 (TEAD3))

Andere Bezeichnung: TEAD3 (TEAD3 Produkte)

Synonyme: DTEF-1 antikoerper, TEF-5 antikoerper, ETFR-1 antikoerper, TEAD-3 antikoerper, TEAD5 antikoerper, TEF5 antikoerper, Tcf13r2 antikoerper, cb882 antikoerper, tead3 antikoerper, TEA domain transcription factor 3 antikoerper, TEA domain family member 3 antikoerper, TEA domain family member 3 a antikoerper, tubby like protein 1 antikoerper, TEAD3 antikoerper, Tead3 antikoerper, tead3a antikoerper, TULP1 antikoerper

Hintergrund:

Background: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer.

Aliases: DTEF 1 antibody, DTEF-1 antibody, DTEF1 antibody, ETFR 1 antibody, ETFR1 antibody, TEA domain family member 3 antibody, TEA domain family member 5 antibody, TEAD 3 antibody, TEAD-3 antibody, Tead3 antibody, TEAD3_HUMAN antibody, TEAD5 antibody, TEF 5 antibody, TEF5 antibody, Transcriptional enhancer factor 5 antibody, Transcriptional enhancer factor TEF 5 (DTEF 1) antibody, Transcriptional enhancer factor TEF 5 antibody, Transcriptional enhancer factor TEF-5 antibody

UniProt: Q99594

Pathways: Regulation of Lipid Metabolism by PPARalpha