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TEAD4 Antikörper (AA 74-434) (HRP)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TEAD4 in ELISA. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7172762

Kurzübersicht für TEAD4 Antikörper (AA 74-434) (HRP) (ABIN7172762)

Target

Alle TEAD4 Antikörper anzeigen
TEAD4 (TEA Domain Family Member 4 (TEAD4))

Reaktivität

  • 44
  • 25
  • 22
  • 6
  • 6
  • 6
  • 5
  • 5
  • 4
  • 3
  • 1
  • 1
Human

Wirt

  • 39
  • 5
Kaninchen

Klonalität

  • 40
  • 4
Polyklonal

Konjugat

  • 27
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser TEAD4 Antikörper ist konjugiert mit HRP

Applikation

  • 42
  • 13
  • 12
  • 9
  • 6
  • 4
  • 2
  • 1
  • 1
  • 1
ELISA
  • Bindungsspezifität

    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 74-434

    Kreuzreaktivität

    Human

    Aufreinigung

    >95%, Protein G purified

    Immunogen

    Recombinant Human Transcriptional enhancer factor TEF-3 protein (74-434AA)

    Isotyp

    IgG
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    TEAD4 (TEA Domain Family Member 4 (TEAD4))

    Andere Bezeichnung

    TEAD4

    Hintergrund

    Background: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC \'enhansons\' (5\'-GTGGAATGT-3\') and activates transcription. Binds to the M-CAT motif.

    Aliases: EFTR 2 antibody, EFTR2 antibody, hRTEF 1B antibody, hRTEF1B antibody, MGC9014 antibody, OTTHUMP00000238119 antibody, OTTHUMP00000238122 antibody, OTTHUMP00000238124 antibody, Related to TEF 1 antibody, Related to TEF1 antibody, Related transcription enhancer factor 1B antibody, RTEF1 antibody, TCF13L1 antibody, TEA domain family member 4 antibody, TEAD 4 antibody, TEAD-4 antibody, TEAD4 antibody, TEAD4_HUMAN antibody, TEF 3 antibody, TEF3 antibody, TEFR 1 antibody, TEFR1 antibody, Transcription factor 13 (SV40 transcriptional enhancer factor) like 1 antibody, Transcription factor 13 like 1 antibody, Transcription factor 13-like 1 antibody, Transcription factor RTEF 1 antibody, Transcription factor RTEF-1 antibody, Transcription factor RTEF1 antibody, Transcriptional enhancer factor 1 related antibody, Transcriptional enhancer factor 3 antibody, Transcriptional enhancer factor TEF 3 antibody, Transcriptional enhancer factor TEF-3 antibody, Transcriptional enhancer factor TEF3 antibody

    UniProt

    Q15561

    Pathways

    Regulation of Lipid Metabolism by PPARalpha
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