TEAD4 Antikörper (AA 74-434) (HRP)

Produktnummer ABIN7172762

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TEAD4 in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TEAD4 Antikörper (AA 74-434) (HRP) (ABIN7172762)

Target: TEAD4 (TEA Domain Family Member 4 (TEAD4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TEAD4 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Produktdetails anti-TEAD4 Antikörper (HRP)

Bindungsspezifität: AA 74-434

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Transcriptional enhancer factor TEF-3 protein (74-434AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TEAD4

Target: TEAD4 (TEA Domain Family Member 4 (TEAD4))

Andere Bezeichnung: TEAD4

Hintergrund:

Background: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC \'enhansons\' (5\'-GTGGAATGT-3\') and activates transcription. Binds to the M-CAT motif.

Aliases: EFTR 2 antibody, EFTR2 antibody, hRTEF 1B antibody, hRTEF1B antibody, MGC9014 antibody, OTTHUMP00000238119 antibody, OTTHUMP00000238122 antibody, OTTHUMP00000238124 antibody, Related to TEF 1 antibody, Related to TEF1 antibody, Related transcription enhancer factor 1B antibody, RTEF1 antibody, TCF13L1 antibody, TEA domain family member 4 antibody, TEAD 4 antibody, TEAD-4 antibody, TEAD4 antibody, TEAD4_HUMAN antibody, TEF 3 antibody, TEF3 antibody, TEFR 1 antibody, TEFR1 antibody, Transcription factor 13 (SV40 transcriptional enhancer factor) like 1 antibody, Transcription factor 13 like 1 antibody, Transcription factor 13-like 1 antibody, Transcription factor RTEF 1 antibody, Transcription factor RTEF-1 antibody, Transcription factor RTEF1 antibody, Transcriptional enhancer factor 1 related antibody, Transcriptional enhancer factor 3 antibody, Transcriptional enhancer factor TEF 3 antibody, Transcriptional enhancer factor TEF-3 antibody, Transcriptional enhancer factor TEF3 antibody

UniProt: Q15561

Pathways: Regulation of Lipid Metabolism by PPARalpha