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Tenascin R Antikörper (AA 1231-1319)

Dieses Anti-Tenascin R-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Tenascin R in ELISA und IHC. Geeignet für Human.
Produktnummer ABIN7171750

Kurzübersicht für Tenascin R Antikörper (AA 1231-1319) (ABIN7171750)

Target

Alle Tenascin R (TNR) Antikörper anzeigen
Tenascin R (TNR) (Tenascin R (Restrictin, Janusin) (TNR))

Reaktivität

  • 38
  • 17
  • 14
  • 1
  • 1
Human

Wirt

  • 37
  • 3
  • 2
Kaninchen

Klonalität

  • 40
  • 2
Polyklonal

Konjugat

  • 18
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Tenascin R Antikörper ist unkonjugiert

Applikation

  • 13
  • 13
  • 13
  • 13
  • 10
  • 6
  • 4
  • 3
  • 3
  • 2
  • 1
ELISA, Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 15
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1231-1319

    Kreuzreaktivität

    Human

    Aufreinigung

    >95%, Protein G purified

    Immunogen

    Recombinant Human Tenascin-R protein (1231-1319AA)

    Isotyp

    IgG
  • Applikationshinweise

    Recommended dilution: IHC:1:500-1:1000,

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    Tenascin R (TNR) (Tenascin R (Restrictin, Janusin) (TNR))

    Andere Bezeichnung

    TNR

    Hintergrund

    Background: Neural extracellular matrix (ECM) protein involved in interactions with different cells and matrix components. These interactions can influence cellular behavior by either evoking a stable adhesion and differentiation, or repulsion and inhibition of neurite growth. Binding to cell surface gangliosides inhibits RGD-dependent integrin-mediated cell adhesion and results in an inhibition of PTK2/FAK1 (FAK) phosphorylation and cell detachment. Binding to membrane surface sulfatides results in a oligodendrocyte adhesion and differentiation. Interaction with CNTN1 induces a repulsion of neurons and an inhibition of neurite outgrowth. Interacts with SCN2B may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier. TNR-linked chondroitin sulfate glycosaminoglycans are involved in the interaction with FN1 and mediate inhibition of cell adhesion and neurite outgrowth. The highly regulated addition of sulfated carbohydrate structure may modulate the adhesive properties of TNR over the course of development and during synapse maintenance (By similarity).

    Aliases: Janusin antibody, MGC149328 antibody, Restrictin antibody, Tenascin R (restrictin, janusin) antibody, Tenascin-R antibody, TENR_HUMAN antibody, TN-R antibody, Tnr antibody

    UniProt

    Q92752

    Pathways

    Regulation of Cell Size
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