TBC1D7 Antikörper (AA 1-293) (Biotin)

Produktnummer ABIN7171659

Der Kaninchen Polyklonal Anti-TBC1D7-Antikörper wurde für ELISA validiert. Er ist geeignet, TBC1D7 in Proben von Human zu detektieren.

Kurzübersicht für TBC1D7 Antikörper (AA 1-293) (Biotin) (ABIN7171659)

Target: TBC1D7 (TBC1 Domain Family, Member 7 (TBC1D7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TBC1D7 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-TBC1D7 Antikörper (Biotin)

Bindungsspezifität: AA 1-293

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human TBC1 domain family member 7 protein (1-293AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TBC1D7

Target: TBC1D7 (TBC1 Domain Family, Member 7 (TBC1D7))

Andere Bezeichnung: TBC1D7

Hintergrund:

Background: Component of the TSC-TBC complex, that contains TBC1D7 in addition to the TSC1-TSC2 complex and consists of the functional complex possessing GTPase-activating protein (GAP) activity toward RHEB in response to alterations in specific cellular growth conditions. The small GTPase RHEB is a direct activator of the protein kinase activity of mTORC1 and the TSC-TBC complex acts as a negative regulator of mTORC1 signaling cascade by acting as a GAP for RHEB. Participates in the proper sensing of growth factors and glucose, but not amino acids, by mTORC1. It is unclear whether TBC1D7 acts as a GTPase-activating protein and additional studies are required to answer this question.

Aliases: TBC1D7 antibody, TBC7 antibody, HSPC239 antibody, TBC1 domain family member 7 antibody, Cell migration-inducing protein 23 antibody

UniProt: Q9P0N9