TIAM2 Antikörper (AA 1500-1627) (Biotin)

Produktnummer ABIN7171463

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TIAM2 in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TIAM2 Antikörper (AA 1500-1627) (Biotin) (ABIN7171463)

Target: TIAM2 (T-Cell Lymphoma Invasion and Metastasis 2 (TIAM2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIAM2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-TIAM2 Antikörper (Biotin)

Bindungsspezifität: AA 1500-1627

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human T-lymphoma invasion and metastasis-inducing protein 2 protein (1500-1627AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TIAM2

Target: TIAM2 (T-Cell Lymphoma Invasion and Metastasis 2 (TIAM2))

Andere Bezeichnung: TIAM2

Hintergrund:

Background: Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Mediates extracellular laminin signals to activate Rac1, contributing to neurite growth. Involved in lamellipodial formation and advancement of the growth cone of embryonic hippocampal neurons. Promotes migration of neurons in the cerebral cortex. When overexpressed, induces membrane ruffling accompanied by the accumulation of actin filaments along the altered plasma membrane (By similarity). Activates specifically RAC1, but not CDC42 and RHOA.

Aliases: FLJ41865 antibody, OTTHUMP00000017472 antibody, SIF and TIAM1 like exchange factor antibody, SIF and TIAM1-like exchange factor antibody, STEF antibody, T cell lymphoma invasion and metastasis 2 antibody, T lymphoma invasion and metastasis inducing protein 2 antibody, T-lymphoma invasion and metastasis-inducing protein 2 antibody, TIAM 2 antibody, TIAM-2 antibody, Tiam2 antibody, TIAM2_HUMAN antibody

UniProt: Q8IVF5

Pathways: Neurotrophin Signalübertragung, Regulation of Lipid Metabolism by PPARalpha