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STAMBP Antikörper (AA 1-424)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch STAMBP in WB, ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7170686

Kurzübersicht für STAMBP Antikörper (AA 1-424) (ABIN7170686)

Target

Alle STAMBP Antikörper anzeigen
STAMBP (STAM Binding Protein (STAMBP))

Reaktivität

  • 46
  • 34
  • 22
  • 6
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
Human

Wirt

  • 59
  • 4
Kaninchen

Klonalität

  • 59
  • 4
Polyklonal

Konjugat

  • 32
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser STAMBP Antikörper ist unkonjugiert

Applikation

  • 38
  • 20
  • 20
  • 13
  • 13
  • 9
  • 8
  • 7
  • 4
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 15
    • 8
    • 8
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-424

    Kreuzreaktivität

    Human

    Aufreinigung

    >95%, Protein G purified

    Immunogen

    Recombinant Human STAM-binding protein (1-424AA)

    Isotyp

    IgG
  • Applikationshinweise

    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    STAMBP (STAM Binding Protein (STAMBP))

    Andere Bezeichnung

    STAMBP

    Hintergrund

    Background: Zinc metalloprotease that specifically cleaves \\\'Lys-63\\\'-linked polyubiquitin chains. Does not cleave \\\'Lys-48\\\'-linked polyubiquitin chains.Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization .Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways.

    Aliases: AMSH antibody, Associated molecule with the SH3 domain of STAM antibody, Endosome associated ubiquitin isopeptidase antibody, Endosome-associated ubiquitin isopeptidase antibody, MGC126516 antibody, MGC126518 antibody, MICCAP antibody, STABP_HUMAN antibody, STAM binding protein antibody, STAM-binding protein antibody, Stambp antibody

    UniProt

    O95630
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