OBFC2A Antikörper (AA 1-204) (Biotin)

Produktnummer ABIN7170413

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch OBFC2A in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für OBFC2A Antikörper (AA 1-204) (Biotin) (ABIN7170413)

Target: OBFC2A (Oligonucleotide/oligosaccharide-Binding Fold Containing 2A (OBFC2A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OBFC2A Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-OBFC2A Antikörper (Biotin)

Bindungsspezifität: AA 1-204

Verwendungszweck: NABP1 Antibody, Biotin conjugated

Aufreinigung: Protein G purified

Reinheit: >95 %

Immunogen: Recombinant Human SOSS complex subunit B2 protein (1-204AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu OBFC2A

Target: OBFC2A (Oligonucleotide/oligosaccharide-Binding Fold Containing 2A (OBFC2A))

Andere Bezeichnung: NABP1

Hintergrund:

Background: Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.

Aliases: FLJ13624 antibody, FLJ22833 antibody, hSSB2 antibody, MGC111163 antibody, Nabp1 antibody, Nucleic acid-binding protein 1 antibody, OBFC2A antibody, Oligonucleotide/oligosaccharide binding fold containing 2A antibody, Oligonucleotide/oligosaccharide binding fold containing protein 2A antibody, Oligonucleotide/oligosaccharide-binding fold-containing protein 2A antibody, Sensor of single strand DNA complex subunit B2 antibody, Sensor of single-strand DNA complex subunit B2 antibody, Sensor of ssDNA subunit B2 antibody, Single stranded DNA binding protein 2 antibody, Single-stranded DNA-binding protein 2 antibody, SOSB2_HUMAN antibody, SOSS B2 antibody, SOSS complex subunit B2 antibody, SOSS-B2 antibody, SSB2 antibody

UniProt: Q96AH0