ICK Antikörper (AA 150-275)

Produktnummer ABIN7169051

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ICK in WB, ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ICK Antikörper (AA 150-275) (ABIN7169051)

Target: ICK (Intestinal Cell (MAK-Like) Kinase (ICK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ICK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-ICK Antikörper

Bindungsspezifität: AA 150-275

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Serine/threonine-protein kinase ICK protein (150-275AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ICK

Target: ICK (Intestinal Cell (MAK-Like) Kinase (ICK))

Andere Bezeichnung: ICK

Hintergrund:

Background: Required for ciliogenesis (PubMed:24797473). Phosphorylates KIF3A (By similarity). Involved in the control of ciliary length (PubMed:24853502). Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips (By similarity). May play a key role in the development of multiple organ systems and particularly in cardiac development (By similarity). Regulates intraflagellar transport (IFT) speed and negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner and this regulation requires its kinase activity (By similarity).

Aliases: CILK1 antibody, ICK antibody, KIAA0936Serine/threonine-protein kinase ICK antibody, EC 2.7.11.1 antibody, Ciliogenesis associated kinase 1 antibody, Intestinal cell kinase antibody, hICK antibody, Laryngeal cancer kinase 2 antibody, LCK2 antibody, MAK-related kinase antibody, MRK antibody

UniProt: Q9UPZ9