HTRA2 Antikörper (AA 334-458) (HRP)

Produktnummer ABIN7168924

Dieses Anti-HTRA2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HTRA2 in ELISA. Geeignet für Human.

Kurzübersicht für HTRA2 Antikörper (AA 334-458) (HRP) (ABIN7168924)

Target: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HTRA2 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Produktdetails anti-HTRA2 Antikörper (HRP)

Bindungsspezifität: AA 334-458

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Serine protease HTRA2, mitochondrial protein (334-458AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu HTRA2

Target: HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

Andere Bezeichnung: HTRA2

Hintergrund:

Background: Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Cleaves THAP5 and promotes its degradation during apoptosis. Isoform 2 seems to be proteolytically inactive.

Aliases: High temperature requirement protein A2 antibody, HTRA 2 antibody, HtrA like serine protease antibody, HtrA serine peptidase 2 antibody, HtrA, E. coli, homolog of, 2 antibody, HtrA2 antibody, HTRA2_HUMAN antibody, mitochondrial antibody, Omi stress regulated endoprotease antibody, Omi stress-regulated endoprotease antibody, PARK 13 antibody, PARK13 antibody, Protease serine 25 antibody, PRSS 25 antibody, PRSS25 antibody, Serine protease 25 antibody, Serine protease HTRA2 antibody, Serine protease HTRA2 mitochondrial antibody, Serine protease htra2 mitochondrial precursor antibody, Serine protease omi antibody, Serine proteinase OMI antibody

UniProt: O43464

Pathways: Positive Regulation of Endopeptidase Activity