Septin 2 Antikörper (AA 1-361)

Produktnummer ABIN7168865

Produktdetails anti-Septin 2 Antikörper

Target: Septin 2 (SEPT2)

Bindungsspezifität: AA 1-361

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Septin 2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Septin-2 protein (1-361AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Septin 2

Target: Septin 2 (SEPT2)

Andere Bezeichnung: SEPT2 (SEPT2 Produkte)

Synonyme: DIFF6 antikoerper, NEDD5 antikoerper, Pnutl3 antikoerper, hNedd5 antikoerper, AW208991 antikoerper, Nedd-5 antikoerper, Nedd5 antikoerper, mKIAA0158 antikoerper, Vesp11 antikoerper, nedd5 antikoerper, wu:fb52g01 antikoerper, wu:fb99a01 antikoerper, Septin-2A antikoerper, Septin-A antikoerper, diff6 antikoerper, pnutl3 antikoerper, sept2 antikoerper, septa antikoerper, xlsepta antikoerper, SEPT2 antikoerper, Sep-02 antikoerper, Septin-2B antikoerper, hnedd5 antikoerper, sept2-B antikoerper, Septin-2 antikoerper, septin 2 antikoerper, septin 2 L homeolog antikoerper, septin 2-like antikoerper, COG1487; VapC; putative nucleic acid-binding protein; contains PIN domain antikoerper, septin 2 S homeolog antikoerper, SEPT2 antikoerper, Sept2 antikoerper, sept2 antikoerper, sept2.L antikoerper, SEPT2L antikoerper, sepT2 antikoerper, sept2.S antikoerper

Hintergrund:

Background: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes: probably acts by regulating the assembly of the tectonic-like complex (also named B9 complex) by localizing TMEM231 protein. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.

Aliases: SEPTIN2 antibody, DIFF6 antibody, KIAA0158 antibody, NEDD5 antibody, SEPT2 antibody, Septin-2 antibody, Neural precursor cell expressed developmentally down-regulated protein 5 antibody, NEDD-5 antibody

UniProt: Q15019