SLFN11 Antikörper (AA 670-821) (Biotin)

Produktnummer ABIN7168623

Der Kaninchen Polyklonal Anti-SLFN11-Antikörper wurde für ELISA validiert. Er ist geeignet, SLFN11 in Proben von Human zu detektieren.

Kurzübersicht für SLFN11 Antikörper (AA 670-821) (Biotin) (ABIN7168623)

Target: SLFN11 (Schlafen Family Member 11 (SLFN11))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLFN11 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-SLFN11 Antikörper (Biotin)

Bindungsspezifität: AA 670-821

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Schlafen family member 11 protein (670-821AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SLFN11

Target: SLFN11 (Schlafen Family Member 11 (SLFN11))

Andere Bezeichnung: SLFN11

Hintergrund:

Background: Interferon (IFN)-induced antiviral protein which acts as an inhibitor of retrovirus protein synthesis. Specifically abrogates the production of retroviruses such as human immunodeficiency virus 1 (HIV-1) by acting as a specific inhibitor of the synthesis of retroviruses encoded proteins in a codon-usage-dependent manner. Binds to tRNAs and exploits the unique viral codon bias towards A/T nucleotides. The exact inhibition mechanism is unclear: may either sequesters tRNAs, prevents their maturation via post-transcriptional processing or accelerates their deacylation. Does not inhibit reverse transcription, integration or production and nuclear export of viral RNA. May play a role in cell cycle arrest and/or induction of apoptosis in response to exogenously induced DNA damage.

Aliases: SLFN11 antibody, Schlafen family member 11 antibody, EC 3.6.-.- antibody

UniProt: Q7Z7L1