CD163 Antikörper (AA 801-940) (HRP)

Produktnummer ABIN7168621

Dieses Anti-CD163-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CD163 in ELISA. Geeignet für Human.

Kurzübersicht für CD163 Antikörper (AA 801-940) (HRP) (ABIN7168621)

Target: CD163

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD163 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Produktdetails anti-CD163 Antikörper (HRP)

Bindungsspezifität: AA 801-940

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Scavenger receptor cysteine-rich type 1 protein M130 protein (801-940AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CD163

Target: CD163

Andere Bezeichnung: CD163

Hintergrund:

Background: Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. May play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. Binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH -dependent manner. Exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1. Isoform 3 exhibits the higher capacity for ligand endocytosis and the more pronounced surface expression when expressed in cells.

Aliases: C163A_HUMAN antibody, CD 163 antibody, CD163 antibody, CD163 antigen antibody, CD163 Molecule antibody, Hemoglobin scavenger receptor antibody, M130 antibody, M130 antigen precursor antibody, Macrophage associated antigen antibody, MM130 antibody, OTTHUMP00000238617 antibody, OTTHUMP00000238618 antibody, OTTHUMP00000238619 antibody, OTTHUMP00000238620 antibody, SCARI1 antibody, Scavenger receptor cysteine rich type 1 protein M130 antibody, sCD163 antibody, Soluble CD163 antibody

UniProt: Q86VB7