ARHGEF5 Antikörper (AA 433-507)

Produktnummer ABIN7167986

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ARHGEF5 in ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ARHGEF5 Antikörper (AA 433-507) (ABIN7167986)

Target: ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF5 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-ARHGEF5 Antikörper

Bindungsspezifität: AA 433-507

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Rho guanine nucleotide exchange factor 5 protein (433-507AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ARHGEF5

Target: ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))

Andere Bezeichnung: ARHGEF5

Hintergrund:

Background: Guanine nucleotide exchange factor which activates Rho GTPases (PubMed:15601624). Strongly activates RHOA (PubMed:15601624). Also strongly activates RHOB, weakly activates RHOC and RHOG and shows no effect on RHOD, RHOV, RHOQ or RAC1 (By similarity). Involved in regulation of cell shape and actin cytoskeletal organization (PubMed:15601624). Plays a role in actin organization by generating a loss of actin stress fibers and the formation of membrane ruffles and filopodia (PubMed:14662653). Required for SRC-induced podosome formation (By similarity). Involved in positive regulation of immature dendritic cell migration (By similarity).

Aliases: ARHG5_HUMAN antibody, ARHGEF 5 antibody, ARHGEF5 antibody, DKFZp686N1969 antibody, ephexin 3 antibody, Ephexin-3 antibody, GEF 5 antibody, GEF5 antibody, Guanine nucleotide regulatory protein TIM antibody, Oncogene TIM antibody, P60 antibody, p60 TIM antibody, Rho guanine nucleotide exchange factor (GEF) 5 antibody, Rho guanine nucleotide exchange factor 5 antibody, TIM 1 antibody, TIM antibody, TIM1 antibody, Transforming immortalized mammary oncogene antibody

UniProt: Q12774