PDE6D Antikörper (AA 1-150)

Produktnummer ABIN7167776

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PDE6D in ELISA, WB und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PDE6D Antikörper (AA 1-150) (ABIN7167776)

Target: PDE6D (phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE6D Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PDE6D Antikörper

Bindungsspezifität: AA 1-150

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Retinal rod rhodopsin-sensitive cGMP 3\\\',5\\\'-cyclic phosphodiesterase subunit delta protein (1-150AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PDE6D

Target: PDE6D (phosphodiesterase 6D, CGMP-Specific, Rod, delta (PDE6D))

Andere Bezeichnung: PDE6D

Hintergrund:

Background: Promotes the release of prenylated target proteins from cellular membranes (PubMed:9712853). Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location (PubMed:22002721, PubMed:23698361). Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E (PubMed:24166846). Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI) (By similarity). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide dissociation rate (By similarity).

Aliases: 5''-cyclic phosphodiesterase subunit delta antibody, GMP PDE delta antibody, GMP-PDE delta antibody, p17 protein antibody, PDE 6 antibody, PDE 6D antibody, PDE D antibody, PDE6 antibody, PDE6D antibody, PDE6D_HUMAN antibody, PDED antibody, Phosphodiesterase 6D cGMP specific antibody, Phosphodiesterase 6D cGMP specific rod delta antibody, Protein p17 antibody, Retinal rod photoreceptor cGMP phosphodiesterase delta antibody, Retinal rod rhodopsin sensitive cGMP 3' 5' cyclic phosphodiesterase subunit delta antibody, Retinal rod rhodopsin-sensitive cGMP 3'' antibody

UniProt: O43924