RAB7B Antikörper (AA 100-199) (Biotin)

Produktnummer ABIN7167382

Dieses Anti-RAB7B-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RAB7B in ELISA. Geeignet für Human.

Kurzübersicht für RAB7B Antikörper (AA 100-199) (Biotin) (ABIN7167382)

Target: RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB7B Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-RAB7B Antikörper (Biotin)

Bindungsspezifität: AA 100-199

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Ras-related protein Rab-7b protein (100-199AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RAB7B

Target: RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))

Andere Bezeichnung: RAB7B

Hintergrund:

Background: Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway.

Aliases: MGC16212 antibody, MGC9726 antibody, RAB7 antibody, rab7B antibody, RAB7B, member RAS oncogene family antibody, RAB7B_HUMAN antibody, Ras related protein Rab 7b antibody, Ras-related protein Rab-7B antibody

UniProt: Q96AH8