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RAB7B Antikörper (AA 100-199)

Der Rabbit Polyclonal Anti-RAB7B-Antikörper wurde für ELISA, IF validiert. Er ist geeignet, RAB7B in Proben von Human zu detektieren.
Produktnummer ABIN7167381

Kurzübersicht für RAB7B Antikörper (AA 100-199) (ABIN7167381)

Target

Alle RAB7B Antikörper anzeigen
RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))

Reaktivität

  • 23
  • 2
  • 1
Human

Wirt

  • 17
  • 6
Kaninchen

Klonalität

  • 19
  • 4
Polyklonal

Konjugat

  • 15
  • 2
  • 2
  • 2
  • 1
  • 1
Dieser RAB7B Antikörper ist unkonjugiert

Applikation

  • 20
  • 17
  • 2
  • 1
ELISA, Immunofluorescence (IF)
  • Bindungsspezifität

    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    AA 100-199

    Kreuzreaktivität

    Human

    Aufreinigung

    >95%, Protein G purified

    Immunogen

    Recombinant Human Ras-related protein Rab-7b protein (100-199AA)

    Isotyp

    IgG
  • Applikationshinweise

    Recommended dilution: IF:1:50-1:200,

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    RAB7B (RAB7B, Member RAS Oncogene Family (RAB7B))

    Andere Bezeichnung

    RAB7B

    Hintergrund

    Background: Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway.

    Aliases: MGC16212 antibody, MGC9726 antibody, RAB7 antibody, rab7B antibody, RAB7B, member RAS oncogene family antibody, RAB7B_HUMAN antibody, Ras related protein Rab 7b antibody, Ras-related protein Rab-7B antibody

    UniProt

    Q96AH8
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