RAB17 Antikörper (AA 1-212)

Produktnummer ABIN7167233

Produktdetails anti-RAB17 Antikörper

Target: RAB17 (RAB17, Member RAS Oncogene Family (RAB17))

Bindungsspezifität: AA 1-212

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Maus

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Ras-related protein Rab-17 protein (1-212AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RAB17

Target: RAB17 (RAB17, Member RAS Oncogene Family (RAB17))

Andere Bezeichnung: RAB17 (RAB17 Produkte)

Synonyme: RAB17 antikoerper, AW413472 antikoerper, RGD1562478 antikoerper, rab17 antikoerper, RAB17, member RAS oncogene family antikoerper, EDI_278050 antikoerper, EDI_260720 antikoerper, EDI_050010 antikoerper, RAB17 antikoerper, Rab17 antikoerper

Hintergrund:

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in transcytosis, the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. Mainly observed in epithelial cells, transcytosis mediates for instance, the transcellular transport of immunoglobulins from the basolateral surface to the apical surface. Most probably controls membrane trafficking through apical recycling endosomes in a post-endocytic step of transcytosis. Required for melanosome transport and release from melanocytes, it also regulates dendrite and dendritic spine development (By similarity). May also play a role in cell migration.

Aliases: AW413472 antibody, FLJ12538 antibody, OTTHUMP00000164417 antibody, OTTHUMP00000202805 antibody, Rab 17 antibody, Rab17 antibody, RAB17 member RAS oncogene family antibody, RAB17_HUMAN antibody, Ras related protein Rab 17 antibody, Ras related protein Rab17 antibody, Ras-related protein Rab-17 antibody

UniProt: Q9H0T7