RIN1 Antikörper (AA 192-341)
Kurzübersicht für RIN1 Antikörper (AA 192-341) (ABIN7167114)
Target
Alle RIN1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 192-341
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Ras and Rab interactor 1 protein (192-341AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: IF:1:50-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RIN1 (Ras and Rab Interactor 1 (RIN1))
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Andere Bezeichnung
- RIN1
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Hintergrund
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Background: Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.
Aliases: RIN1 antibody, Ras and Rab interactor 1 antibody, Ras inhibitor JC99 antibody, Ras interaction/interference protein 1 antibody
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UniProt
- Q13671
Target
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