PYHIN1 Antikörper (AA 1-245)
Kurzübersicht für PYHIN1 Antikörper (AA 1-245) (ABIN7166880)
Target
Alle PYHIN1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 1-245
-
Kreuzreaktivität
- Human, Maus
-
Aufreinigung
- >95%, Protein G purified
-
Immunogen
- Recombinant Human Pyrin and HIN domain-containing protein 1 protein (1-245AA)
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- Recommended dilution: WB:1:1000-1:5000,
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C,-80 °C
-
Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
-
Andere Bezeichnung
- PYHIN1
-
Hintergrund
-
Background: Major mediator of the tumor suppressor activity of IFN in breast cancer cells. Promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization. Promotes ubiquitination and subsequent degradation of HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.
Aliases: IFIX_HUMAN antibody, Interferon-inducible protein X antibody, Pyhin1 antibody, Pyrin and HIN domain-containing protein 1 antibody
-
UniProt
- Q6K0P9
Target
-