QKI Antikörper (AA 1-341)

Produktnummer ABIN7166001

Der Kaninchen Polyklonal Anti-QKI-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, QKI in Proben von Human zu detektieren.

Kurzübersicht für QKI Antikörper (AA 1-341) (ABIN7166001)

Target: QKI (Protein Quaking (QKI))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser QKI Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-QKI Antikörper

Bindungsspezifität: AA 1-341

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Protein quaking protein (1-341AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu QKI

Target: QKI (Protein Quaking (QKI))

Andere Bezeichnung: QKI

Hintergrund:

Background: RNA-binding protein that plays a central role in myelinization (PubMed:16641098). Binds to the 5\\\'-NACUAAY-N(1,20)-UAAY-3\\\' RNA core sequence. Regulates target mRNA stability (PubMed:23630077). In addition, acts by regulating pre-mRNA splicing, mRNA export and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B. Regulator of oligodendrocyte differentiation and maturation in the brain that may play a role in myelin and oligodendrocyte dysfunction in schizophrenia (PubMed:16641098). Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity).

Aliases: DKFZp586I0923 antibody, HKQ antibody, Homolog of mouse quaking QKI KH domain RNA binding protein antibody, Hqk antibody, HQK1 antibody, HqkI antibody, OTTHUMP00000017581 antibody, OTTHUMP00000017582 antibody, OTTHUMP00000017583 antibody, Protein quaking antibody, QK antibody, QK1 antibody, QK3 antibody, QKI antibody, QKI_HUMAN antibody, QKI1 antibody, Quaking homolog antibody, Quaking homolog KH domain RNA binding antibody, Quaking homolog KH domain RNA binding mouse antibody, Quaking isoform 1 antibody, Quaking protein antibody, RNA binding protein HQK antibody

UniProt: Q96PU8