MTDH Antikörper (AA 1-260)

Produktnummer ABIN7165774

Dieses Anti-MTDH-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von MTDH in IHC, ELISA und IP. Geeignet für Human.

Kurzübersicht für MTDH Antikörper (AA 1-260) (ABIN7165774)

Target: MTDH (Metadherin (MTDH))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MTDH Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Produktdetails anti-MTDH Antikörper

Bindungsspezifität: AA 1-260

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Protein LYRIC protein (1-260AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IP:1:200-1:2000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MTDH

Target: MTDH (Metadherin (MTDH))

Andere Bezeichnung: MTDH

Hintergrund:

Background: Downregulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance.

Aliases: 3D3 antibody, 3D3/LYRIC antibody, AEG 1 antibody, AEG-1 antibody, AEG1 antibody, Astrocyte elevated gene 1 antibody, Astrocyte elevated gene-1 protein antibody, LYRIC antibody, LYRIC/3D3 antibody, LYRIC_HUMAN antibody, Lysine rich CEACAM1 associated protein antibody, Lysine rich CEACAM1 co isolated protein antibody, Lysine-rich CEACAM1 co-isolated protein antibody, Metadherin antibody, Metastasis adhesion protein antibody, MTDH antibody, Protein LYRIC antibody

UniProt: Q86UE4

Pathways: Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization