LIN7A Antikörper (AA 1-233) (Biotin)

Produktnummer ABIN7165759

Dieses Anti-LIN7A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von LIN7A in ELISA. Geeignet für Human.

Kurzübersicht für LIN7A Antikörper (AA 1-233) (Biotin) (ABIN7165759)

Target: LIN7A (Lin-7 Homolog A (LIN7A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LIN7A Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-LIN7A Antikörper (Biotin)

Bindungsspezifität: AA 1-233

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Protein lin-7 homolog A protein (1-233AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu LIN7A

Target: LIN7A (Lin-7 Homolog A (LIN7A))

Andere Bezeichnung: LIN7A

Hintergrund:

Background: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.

Aliases: hLin-7 antibody, Lin 7 homolog A (C. elegans) antibody, LIN 7A antibody, Lin-7A antibody, LIN7 antibody, LIN7A antibody, LIN7A_HUMAN antibody, MALS-1 antibody, Mammalian LIN 7 1 antibody, Mammalian lin-seven protein 1 antibody, Protein lin-7 homolog A antibody, Tax interaction protein 33 antibody, TIP-33 antibody, Veli-1 antibody, VELI1 antibody, Vertebrate lin-7 homolog 1 antibody, Vertebrate LIN7 homolog 1 antibody

UniProt: O14910

Pathways: Synaptic Membrane