IWS1 Antikörper (AA 570-819)

Produktnummer ABIN7165661

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IWS1 in WB, ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für IWS1 Antikörper (AA 570-819) (ABIN7165661)

Target: IWS1 (IWS1 Homolog (IWS1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IWS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-IWS1 Antikörper

Bindungsspezifität: AA 570-819

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Protein IWS1 homolog protein (570-819AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu IWS1

Target: IWS1 (IWS1 Homolog (IWS1))

Andere Bezeichnung: IWS1

Hintergrund:

Background: Transcription factor which plays a key role in defining the composition of the RNA polymerase II (RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription.

Aliases: DKFZp761G0123 antibody, FLJ10006 antibody, FLJ14655 antibody, FLJ32319 antibody, Interacts with Spt6 antibody, iws1 antibody, IWS1 homolog antibody, IWS1-like protein antibody, IWS1_HUMAN antibody, IWS1L antibody, MGC126375 antibody, MGC126376 antibody, OTTHUMP00000162262 antibody, Protein IWS1 homolog antibody

UniProt: Q96ST2