INTU Antikörper (AA 6-139)

Produktnummer ABIN7165653

Der Kaninchen Polyklonal Anti-INTU-Antikörper wurde für ELISA, IF und IHC validiert. Er ist geeignet, INTU in Proben von Human zu detektieren.

Kurzübersicht für INTU Antikörper (AA 6-139) (ABIN7165653)

Target: INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser INTU Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Produktdetails anti-INTU Antikörper

Bindungsspezifität: AA 6-139

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Protein inturned protein (6-139AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu INTU

Target: INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))

Andere Bezeichnung: INTU

Hintergrund:

Background: Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (PubMed:27158779).

Aliases: Homolog of inturned (X. tropicalis) antibody, INT antibody, intu antibody, Inturned planar cell polarity effector homolog antibody, KIAA1284 antibody, PDZ domain containing 6 antibody, PDZ domain-containing protein 6 antibody, PDZD 6 antibody, PDZD6_HUMAN antibody, PDZK6 antibody

UniProt: Q9ULD6