IMPACT Antikörper (AA 41-320) (Biotin)

Produktnummer ABIN7165646

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IMPACT in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für IMPACT Antikörper (AA 41-320) (Biotin) (ABIN7165646)

Target: IMPACT (Impact Homolog (IMPACT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IMPACT Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-IMPACT Antikörper (Biotin)

Bindungsspezifität: AA 41-320

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Protein IMPACT protein (41-320AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu IMPACT

Target: IMPACT (Impact Homolog (IMPACT))

Andere Bezeichnung: IMPACT

Hintergrund:

Background: Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis. May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis. Through its action on GCN2, may also facilitate neuritogenesis.

Aliases: IMPACT antibody, Impact homolog (mouse) antibody, Impact homolog antibody, impact RWD domain protein antibody, IMPCT_HUMAN antibody, Imprinted and ancient gene protein homolog antibody, MGC33718 antibody, Protein IMPACT antibody, RWD domain containing 5 antibody, RWDD5 antibody

UniProt: Q9P2X3