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PRMT1 Antikörper (AA 20-353)

This anti-PRMT1 antibody (ABIN7165065) is a Rabbit Polyclonal antibody detecting PRMT1 in WB, ELISA, IHC. Suitable for Human.
Produktnummer ABIN7165065

Kurzübersicht für PRMT1 Antikörper (AA 20-353) (ABIN7165065)

Target

Alle PRMT1 Antikörper anzeigen
PRMT1 (Protein Arginine Methyltransferase 1 (PRMT1))

Reaktivität

  • 64
  • 36
  • 30
  • 8
  • 6
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 58
  • 6
  • 1
Kaninchen

Klonalität

  • 49
  • 16
Polyklonal

Konjugat

  • 40
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Dieser PRMT1 Antikörper ist unkonjugiert

Applikation

  • 45
  • 31
  • 28
  • 14
  • 8
  • 6
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 10
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 20-353

    Kreuzreaktivität

    Human

    Aufreinigung

    Antigen Affinity Purified

    Immunogen

    Recombinant Human Protein arginine N-methyltransferase 1 protein (20-353AA)

    Isotyp

    IgG
  • Applikationshinweise

    Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    PRMT1 (Protein Arginine Methyltransferase 1 (PRMT1))

    Andere Bezeichnung

    PRMT1

    Hintergrund

    Background: Arginine methyltransferase that methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues present in proteins such as ESR1, histone H2, H3 and H4, PIAS1, HNRNPA1, HNRNPD, NFATC2IP, SUPT5H, TAF15 and EWS. Constitutes the main enzyme that mediates monomethylation and asymmetric dimethylation of histone H4 \\\'Arg-4\\\' (H4R3me1 and H4R3me2a, respectively), a specific tag for epigenetic transcriptional activation. Together with dimethylated PIAS1, represses STAT1 transcriptional activity, in the late phase of interferon gamma (IFN-gamma) signaling. May be involved in the regulation of TAF15 transcriptional activity, act as an activator of estrogen receptor (ER)-mediated transactivation, play a key role in neurite outgrowth and act as a negative regulator of megakaryocytic differentiation, by modulating p38 MAPK pathway. Methylates FOXO1 and retains it in the nucleus increasing its transcriptional activity.

    Aliases: ANM 1 antibody, ANM1 antibody, ANM1_HUMAN antibody, HCP 1 antibody, HCP1 antibody, Heterogeneous nuclear ribonucleoprotein methyltransferase 1 like 2 antibody, Heterogeneous nuclear ribonucleoproteins methyltransferase like 2 antibody, Heterogeneous nuclear ribonucleoproteins methyltransferase like2 antibody, Histone-arginine N-methyltransferase PRMT1 antibody, HMT 2 antibody, HMT1 (hnRNP methyltransferase S. cerevisiae) like 2 antibody, HMT1 hnRNP methyltransferase antibody, HMT1 hnRNP methyltransferase like 2 (S. cerevisiae) antibody, HMT1 hnRNP methyltransferase like 2 antibody, HMT2 antibody, HRMT1 L2 antibody, HRMT1L 2 antibody, HRMT1L2 antibody, Human mRNA for suppressor for yeast mutant antibody, Human mRNA for suppressor for yeast mutant complete cds antibody, Interferon receptor 1 bound protein 4 antibody, Interferon receptor 1 bound protein4 antibody, Interferon receptor 1-bound protein 4 antibody, Interferon receptor 1bound protein 4 antibody, IR1 B4 antibody, IR1B 4 antibody, IR1B4 antibody, Mrmt 1 antibody, Mrmt1 antibody, PRMT 1 antibody, PRMT1 antibody, Protein arginine methyltransferase 1 antibody, Protein arginine N methyltransferase 1 antibody, Protein arginine N methyltransferase1 antibody, Protein arginine N-methyltransferase 1 antibody, R1B4 antibody, S. cerevisiae like 2 antibody

    UniProt

    Q99873
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