RNF212 Antikörper (AA 1-297)

Produktnummer ABIN7164415

Produktdetails anti-RNF212 Antikörper

Target: RNF212 (Ring Finger Protein 212 (RNF212))

Bindungsspezifität: AA 1-297

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF212 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Probable E3 SUMO-protein ligase RNF212 protein (1-297AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu RNF212

Target: RNF212 (Ring Finger Protein 212 (RNF212))

Andere Bezeichnung: RNF212 (RNF212 Produkte)

Synonyme: ZHP3 antikoerper, ring finger protein 212 antikoerper, RNF212 antikoerper

Hintergrund:

Background: SUMO E3 ligase that acts as a regulator of crossing-over during meiosis: required to couple chromosome synapsis to the formation of crossover-specific recombination complexes. Localizes to recombination sites and stabilizes meiosis-specific recombination factors, such as MutS-gamma complex proteins (MSH4 and MSH5) and TEX11. May mediate sumoylation of target proteins MSH4 and/or MSH5, leading to enhance their binding to recombination sites. Acts as a limiting factor for crossover designation and/or reinforcement and plays an antagonist role with CCNB1IP1/HEI10 in the regulation of meiotic recombination (By similarity).

Aliases: FLJ38841 antibody, Hypothetical protein LOC285498 antibody, LOC285498 antibody, OTTHUMP00000147525 antibody, Probable E3 SUMO-protein ligase RNF212 antibody, RING finger protein 212 antibody, RN212_HUMAN antibody, RNF 212 antibody, RNF212 antibody, ZHP3 antibody, ZHP3, C. elegans, homolog of antibody, ZIP3-related protein antibody

UniProt: Q495C1