Plexin B2 Antikörper (AA 1080-1200)
Kurzübersicht für Plexin B2 Antikörper (AA 1080-1200) (ABIN7163708)
Target
Alle Plexin B2 (PLXNB2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1080-1200
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Kreuzreaktivität
- Human, Maus
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Aufreinigung
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Plexin-B2 protein (1080-1200AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Plexin B2 (PLXNB2)
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Andere Bezeichnung
- PLXNB2
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Hintergrund
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Background: Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at \\\'Tyr-1248\\\'. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. Regulates the migration of cerebellar granule cells in the developing brain. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May modulate the activity of RAC1 and CDC42. Down-regulates macrophage migration in wound-healing assays (in vitro) (By similarity).
Aliases: PLXNB2 antibody, KIAA0315 antibody, Plexin-B2 antibody, MM1 antibody
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UniProt
- O15031
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Pathways
- Tube Formation
Target
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