CYP4F2 Antikörper (AA 268-373)

Produktnummer ABIN7163434

Der Kaninchen Polyklonal anti-CYP4F2 Antikörper (ABIN7163434) detektiert spezifisch CYP4F2 in ELISA und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für CYP4F2 Antikörper (AA 268-373) (ABIN7163434)

Target: CYP4F2 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 2 (CYP4F2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP4F2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-CYP4F2 Antikörper

Bindungsspezifität: AA 268-373

Verwendungszweck: CYP4F2 Antibody

Aufreinigung: Protein G purified

Reinheit: >95 %

Immunogen: Recombinant Human Phylloquinone omega-hydroxylase CYP4F2 protein (268-373AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CYP4F2

Target: CYP4F2 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 2 (CYP4F2))

Andere Bezeichnung: CYP4F2

Hintergrund:

Background: Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation (PubMed:19297519, PubMed:24138531). Also shows arachidonic acid omega-hydroxylase activity in kidney, by mediating conversion of arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE), possibly influencing blood pressure control (PubMed:10660572, PubMed:17341693, PubMed:18574070). Also acts as a leukotriene-B(4) omega-hydroxylase by mediating conversion of leukotriene-B(4) (LTB4) to its omega-hydroxylated metabolite 20-hydroxyleukotriene-B(4) (20-OH LTB4) (PubMed:8026587, PubMed:9799565).

Aliases: CYP4F2Cytochrome P450 4F2 antibody, EC 1.14.14.1 antibody, 20-hydroxyeicosatetraenoic acid synthase antibody, 20-HETE synthase antibody, Arachidonic acid omega-hydroxylase antibody, CYPIVF2 antibody, Cytochrome P450-LTB-omega antibody, Docosahexaenoic acid omega-hydroxylase antibody, EC 1.14.14.79 antibody, Leukotriene-B(4) 20-monooxygenase 1 antibody, Leukotriene-B(4) omega-hydroxylase 1 antibody, EC 1.14.14.94 antibody, Phylloquinone omega-hydroxylase CYP4F2 antibody, EC 1.14.14.78 antibody

UniProt: P78329

Pathways: Monocarboxylic Acid Catabolic Process