PTPMT1 Antikörper (AA 28-201)

Produktnummer ABIN7163151

Der Kaninchen Polyklonal Anti-PTPMT1-Antikörper wurde für ELISA, WB und IHC validiert. Er ist geeignet, PTPMT1 in Proben von Human zu detektieren.

Kurzübersicht für PTPMT1 Antikörper (AA 28-201) (ABIN7163151)

Target: PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTPMT1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PTPMT1 Antikörper

Bindungsspezifität: AA 28-201

Kreuzreaktivität: Human, Ratte

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 protein (28-201AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:1000-1:2000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PTPMT1

Target: PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))

Andere Bezeichnung: PTPMT1

Hintergrund:

Background: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells.

Aliases: DUSP23 antibody, FLJ46081 antibody, MOSP antibody, NB4 apoptosis/differentiation related protein antibody, Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 antibody, Phosphoinositide lipid phosphatase antibody, PLIP antibody, PNAS 129 antibody, protein tyrosine phosphatase mitochondrial 1 antibody, Protein-tyrosine phosphatase mitochondrial 1 antibody, pten like phosphatase antibody, PTEN-like phosphatase antibody, PTPM1_HUMAN antibody, Ptpmt1 antibody

UniProt: Q8WUK0

Pathways: Inositol Metabolic Process