Sphingomyelin Synthase 2 Antikörper (AA 1-79) (Biotin)

Produktnummer ABIN7163136

Der Kaninchen Polyklonal Anti-Sphingomyelin Synthase 2-Antikörper wurde für ELISA validiert. Er ist geeignet, Sphingomyelin Synthase 2 in Proben von Human zu detektieren.

Kurzübersicht für Sphingomyelin Synthase 2 Antikörper (AA 1-79) (Biotin) (ABIN7163136)

Target: Sphingomyelin Synthase 2 (SGMS2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Sphingomyelin Synthase 2 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-Sphingomyelin Synthase 2 Antikörper (Biotin)

Bindungsspezifität: AA 1-79

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Phosphatidylcholine:ceramide cholinephosphotransferase 2 protein (1-79AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Sphingomyelin Synthase 2

Target: Sphingomyelin Synthase 2 (SGMS2)

Andere Bezeichnung: SGMS2

Hintergrund:

Background: Sphingomyelin synthases synthesize the sphingolipid, sphingomyelin, through transfer of the phosphatidyl head group, phosphatidylcholine, on to the primary hydroxyl of ceramide. The reaction is bidirectional depending on the respective levels of the sphingolipid and ceramide. Plasma membrane SMS2 can also convert phosphatidylethanolamine (PE) to ceramide phosphatidylethanolamine (CPE). Major form in liver. Required for cell growth in certain cell types. Regulator of cell surface levels of ceramide, an important mediator of signal transduction and apoptosis. Regulation of sphingomyelin (SM) levels at the cell surface affects insulin sensitivity.

Aliases: MGC26963 antibody, Phosphatidylcholine:ceramide cholinephosphotransferase 2 antibody, SGMS 2 antibody, Sgms2 antibody, SM synthase antibody, SMS 2 antibody, SMS2 antibody, SMS2_HUMAN antibody, Sphingomyelin synthase 2 antibody

UniProt: Q8NHU3