PPARA Antikörper (AA 1-237) (FITC)

Produktnummer ABIN7163011

Produktdetails anti-PPARA Antikörper (FITC)

Target: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Bindungsspezifität: AA 1-237

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPARA Antikörper ist konjugiert mit FITC

Applikation: Bitte anfragen

Kreuzreaktivität: Human

Aufreinigung: >95%, Antigen Affinity purified & Affinity purified

Immunogen: Recombinant Human Peroxisome proliferator-activated receptor alpha protein (1-237AA)

Isotyp: IgG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PPARA

Target: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Andere Bezeichnung: PPARA (PPARA Produkte)

Hintergrund:

Background: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.

Aliases: hPPAR antibody, MGC2237 antibody, MGC2452 antibody, NR1C1 antibody, Nuclear receptor subfamily 1 group C member 1 antibody, OTTHUMP00000197740 antibody, OTTHUMP00000197741 antibody, Peroxisome proliferative activated receptor alpha antibody, Peroxisome proliferator activated receptor alpha antibody, Peroxisome proliferator-activated receptor alpha antibody, PPAR antibody, PPAR-alpha antibody, ppara antibody, PPARA_HUMAN antibody, PPARalpha antibody

UniProt: Q07869

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C