PLIN5 Antikörper (AA 305-453)

Produktnummer ABIN7162899

Der Kaninchen Polyklonal Anti-PLIN5-Antikörper wurde für ELISA, WB und IF validiert. Er ist geeignet, PLIN5 in Proben von Human zu detektieren.

Kurzübersicht für PLIN5 Antikörper (AA 305-453) (ABIN7162899)

Target: PLIN5 (Perilipin 5 (PLIN5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLIN5 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-PLIN5 Antikörper

Bindungsspezifität: AA 305-453

Kreuzreaktivität: Human, Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Perilipin-5 protein (305-453AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PLIN5

Target: PLIN5 (Perilipin 5 (PLIN5))

Andere Bezeichnung: PLIN5

Hintergrund:

Background: Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets. Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2. Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE (By similarity).

Aliases: Lipid storage droplet protein 5 antibody, LSDA5 antibody, MLDP antibody, OXPAT antibody, Perilipin 5 antibody, Perilipin-5 antibody, PLIN5 antibody, PLIN5_HUMAN antibody

UniProt: Q00G26